medestheticsmagazine.com | APRIL 2014 71
or duration for aesthetic procedures," says Dr. Cohen,
"but I am excited about the topical neuromodulator
preparations being developed. Physicians don't really
know how signifi cant the needle phobic population may
be, but once a topical preparation is available we may
fi nd new patient populations and potential new uses
of neuromodulators."
RT001 from Revance Therapeutics (revance.com)
is a botulinum toxin type A topical gel that is enter-
ing Phase 3 clinical trials. Phase 2 trials showed no
signifi cant safety issues. There was no evidence of
regional spread of botulinum toxin and no serious
adverse events. Revance is also working on RT002, an
injectable botulinum toxin type A formulation that uses
TransMTS technology to restrict the active molecule to
the target site and reduce unwanted spread.
There's competition here as well. Transdermal Corp.
(transdermalcorp.com), based in Birmingham, Michigan
is testing Cosmetox, a botulinum toxin type A topical
cream delivered with the company's proprietary non-
particle drug delivery technology.
Both of these products and the rationale behind
topical delivery of botulinum toxin is well covered in
"Topical Botulinum Toxins" by Ashley Collins, MD, and
Adnan Nasir, MD, published in the March 2010 issue of
the Journal of Clinical and Aesthetic Dermatology.
As new products enter the market, physicians are
fi nding more ways to use these products both for cos-
metic and medical purposes. "We offer extended hours
for Botox injections, called Technology Thursday," says
Dr. Narurkar. "We call it this, since San Francisco is a
new technology hub. We stay open on Thursdays from
5pm to 7pm to accommodate people after work." He
has been amazed by the turnout of new patients: "We
are booked solid for an hour and a half every week with
new patients. We are also seeing younger patients and
more men. And we still haven't hit the masses."
Linda W. Lewis is the contributing editor of MedEsthetics.
"Diffusion can be dose
related or related to the
reconstitution volume."
THE POWER OF THREE
continued from page 40
Allergan Inc./BOTOX Cosmetic ......... 16-19
800.268.6963 botoxcosmetic.com
Alma Lasers, Ltd. ..................................... 45
224.377.2010 almalasers.com
Amiea Med .............................................. 29
877.628.7201 amieamed.com
Clinicians Complex .................................. 37
800.826.4480 clinicianscomplex.com
CLS-Surgimedics ...................................... 11
800.645.7418 surgimedics.com
DCL Skincare/Dermatologic Cosmetic Labs
............................................................ 13
800.552.5060 dclskincare.com
Ellman International, Inc. ........................ 2-3
516.594.3333 ellman.com
EltaMD/Swiss-American Products, Inc.
..................................... Inside Back Cover
800.633.8872 eltamd.com
Environ/Dermaconcepts .......................... 15
508.539.8900 dermaconcepts.com
FotoFinder Systems, Inc. ......................... 49
888.501.0805 fotofi nder-systems.com
GMC Medical ........................................... 55
844.789.1802 gmcmedicalskincare.com
Hale Cosmeceuticals ............................... 31
800.951.7005 halecosmeceuticals.com
HydroPeptide .......................................... 51
800.932.9873 hydropeptide.com
Lumenis ................................................... 41
877.764.9707 aesthetic.lumenis.com
Medi-Weightloss Clinics ........................... 39
866.551.6334 mediweightlossfranchising.com
Merz Aesthetics ....................................... 33
336.217.2300 merzusa.com
Merz Pharmaceuticals/Xeomin ............... 4-7
336.217.2300 xeominaesthetic.com
Modernizing Medicine Inc. ....................... 35
561.880.2998 modmed.com
NeoStrata Company, Inc.............Back Cover
800.628.9904 neostratapro.com
Nouveau Contour USA, Inc. .................... 28
877.628.7201 nouveaucontour.com
PhytoCeuticals .................................... 22-23
877.474.9862 myphyto-c.com
Premiere Beauty Show ............................ 67
800.335.7469 premieredayspa.biz
ReachLocal, Inc. ....................................... 65
888.966.9735 reachlocal.com
Revitalash/Athena Cosmetics ................... 53
877.909.5274 revitalash.com
Sciton ............................... Inside Front Cover
888.646.6999 sciton.com
Skinprint .................................................. 25
800.234.1308 skinprint.com
Vegas Cosmetic Surgery Show ................ 69
vegascosmeticsurgery.info
Viscot Medical .......................................... 27
800.221.0658 viscot.com
Young Pharmaceuticals ............................ 47
800.874.9686 youngpharm.com
ZO Skin Health ....................................... 8-9
949.988.7524 zoskinhealth.com
AD INDEX
P o w e r o f T h r e e / A d I n d e x M E D 4 1 4 . i n d d 7 1 Power of Three/Ad Index MED414.indd 71 3 / 1 8 / 1 4 1 2 : 4 1 P M 3/18/14 12:41 PM