Medesthetics

SEP 2017

MedEsthetics—business education for medical practitioners—provides the latest noninvasive cosmetic procedures, treatment trends, product and equipment reviews, legal issues and medical aesthetics industry news.

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66 SEPTEMBER 2017 | Med Esthetics GOLDMAN NAMED CHAIRMAN OF CALECIM ADVISORY BOARD San Diego-based der- matologist Mitchel P. Goldman, MD, has been named chairman of the Calecim Professional Medical Advisory Board. The Calecim Professional skincare line is manufac- tured by CellResearch Corporation, a Singapore- based biotech company that discovered a source of stem cells in the umbilical cord lining in 2004. This discovery is patent-protected in 41 territories worldwide. Apart from the Calecim Professional line, which utilizes the stem cells, the company also owns CordLabs, which licenses cord-lining stem cell banking technology to cord blood and tissue banks. CellResearch is also actively formulating a cord-lining stem cell-based wound-healing drug that is undergoing U.S. FDA trials for use on chronic diabetic and other hard-to-heal wounds. Dr. Goldman is currently conducting an Institutional Review Board (IRB)-approved clinical trial using Calecim Professional Multi-Action Cream. He will also help co-devel- opment new Calecim technology products and applications. "This is exciting news for both Calecim and CellResearch," said Gavin Tan, CEO of CellResearch Corporation. "With Dr. Goldman, we're partnered with the 'grandfather' of growth factors, if you will, and our research aims to provide patients with a solution for a variety of skin concerns." R ESEA RCH ERS I DENTI FY M ECH A N ISM TH AT CAUSES GR AY H A I R A N D BA L DI NG Researchers at UT Southwestern Medical Center have identified the cells that directly give rise to hair as well as the mechanism that causes hair to turn gray—findings that could one day help identify possible treatments for balding and hair graying. "Although this project was started in an effort to under- stand how certain kinds of tumors form, we ended up learn- ing why hair turns gray and discovering the identity of the cell that directly gives rise to hair," said Lu Le, MD, PhD, associ- ate professor of dermatology with the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern and one of the authors of study, which was published in Genes and Development (May 2017). "With this knowledge, we hope in the future to create a topical compound or to safely deliver the necessary gene to hair follicles to correct these cosmetic problems." While studying Neurofi bromatosis Type 1, a rare genetic disease that causes tumors to grow on nerves, the research- ers found that a protein called KROX20, more commonly associated with nerve development, turns on in skin cells that become the hair shaft. These hair progenitor cells then produce a protein called stem cell factor (SCF) that the researchers showed is essential for hair pigmentation. When they deleted the SCF gene in the hair progenitor cells in mouse models, the animal's hair turned white. When they deleted the KROX20-producing cells, no hair grew and the mice became bald, according to the study. The researchers will now try to fi nd out if the KROX20 in cells and the SCF gene stop working properly as people age, leading to the graying and hair thinning seen in older people. PLASTIC SU RGEON JOI NS DOM ESTIC A BUSE A DV ISORY COU NCI L Benjamin Stong, MD, of Kalos Facial Plastic Surgery in Atlanta has been appointed to the Cosmetic and Reconstructive Support Medical Advisory Council of the National Coalition Against Domestic Violence (NCADV). The program works in collaboration with the American Academy of Facial Plastic and Reconstructive Surgery (AAFPRS) to provide reconstructive care for domestic abuse survivors. "I feel privileged and honored to be chosen by the NCADV," said Dr. Stong. "Being invited to use my experience and expertise in plastic surgery to assist survivors of domestic abuse move towards a brighter future is such a rewarding and honorable opportunity." "I am excited to have Dr. Stong join me on the NCADV Advisory Council," said facial plastic surgeon Ben Talei, MD, of the Beverly Hills Center. "He is one of the best in the nation, and I know he will make a tremendous contribution towards our special mission to help the victims of domestic abuse." To learn more about The National Coalition Against Domes- tic Violence, visit ncadv.org. ALLERGAN TO ACQUIRE KELLER Allergan has announced its plans to acquire Keller Medical, a privately held medical device company that developed the Keller Funnel in 2009. The cone-shaped, lubricated plastic funnel assists plastic surgeons in breast augmentation and re- construction procedures by guiding silicone gel implants into the surgical pocket. It allows surgeons to use a "no-touch" technique, which may help minimize the introduction of bacteria and foreign material into the surgical pocket. "Allergan is focused on providing technologies and prod- ucts to help our surgeon customers improve procedures, NEWS & EVENTS Mitchel P. Goldman, MD

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